Kimberly Fiock, MS

Kimberly Fiock
Graduate Student
kimberly-fiock@uiowa.edu
 

Department of Pathology
1020B/1A Medical Laboratories
500 Newton Road
University of Iowa
Iowa City, IA 52242-1109

Lab: 319-335-8427

Education

BS, Neuroscience and Psychology, University of Texas at Dallas
MS, Pathology, The University of Iowa

Research

I graduated in May 2018 with my Bachelor of Science in Neuroscience and Psychology from the University of Texas at Dallas. As an undergrad, I did a summer internship in the neuropathology lab of Dr. Thomas Beach, which sparked my interest in studying neurodegenerative tauopathies. My thesis work in the lab of Dr. Marco Hefti focuses on mapping the expression, phosphorylation, and splicing pattern of the protein tau in the developing human brain, as well as within potential model species like mice, pigs, and cats. Because tau is highly implicated in numerous neurodegenerative diseases, it is essential to understand the complex role tau plays in neuronal maturation and axonal growth to help with identifying mechanisms regulating the onset of tau transcription and suppressing translation, as this may provide potential therapeutic targets for neurodegenerative tauopathies.

Publications

  1. Liu G, Fiock KL, Levites Y, Golde TE, Hefti MM, Lee G. Fyn depletion ameliorates tauP301L-induced neuropathology. Acta Neuropathol Commun. 2020; 8(1):108. https://doi.org/10.1186/s40478-020-00979-6

  2. Fiock, KL, Smalley, ME, Crary, JF, Pasca, AM, Hefti MM. Increased Tau Expression Correlates with Neuronal Maturation in the Developing Human Cerebral Cortex. eNeuro. 2020; 1-9. https://doi.org/10.1523/ENEURO.0058-20.2020

  3. Fiock, KL,  Smith, JD,  Crary, JF,  Hefti, MM.  β‐amyloid and tau pathology in the aging feline brain. J Comp Neurol.  2019; 1– 6. https://doi.org/10.1002/cne.24741

  4. Hefti, MM, Kim, SH, Bell, AJ, Betters, RK, Fiock, KL, Iida, MA, Smalley, ME, Farrell, K, Fowkes, ME, Crary, JF. Tau Phosphorylation and Aggregation in the Developing Human Brain. J Neuropathol Exp Neurol. 2019; 1-9. https://doi.org/10.1093/jnen/nlz073